Cosmetic Therapies

Face Lifting   Breast Augmentation    
 

Face Lifting

A face lift or face rejuvenation is a type of cosmetic surgery procedure used to give or restore a more youthful appearance and also restore facial geometry and skin appearance. It is also known as a rhytidectomy.

Wrinkles can take hold in different parts of the face on different people as an aging effect. Some people develop deep creases between the nose and mouth, while others see the skin around their lower jaw and neck is getting weak and loose. The procedures which can be effectively removed these aging effect is more commonly known as a face lift.


There are set of  surgical procedure for face lifting and apart from that various other method like Botox injection, collegenase injection, chemical peeling normally used for face lifting. In recent days people are using stem cells for face lifting as it is hypothesized that adult Stem Cells derived from adipose tissue can be a source for producing other “hormone-like” substances to enhance both skin quality and the underlying subcutaneous- fatty tissues of the cheeks, the mid face and the skin in general.  The result is a long-term marked improvement that enhances both skin quality as well as the underlying youthful contours of the face. The combination of stem cell therapy with the lipostructure technique, can enhance tissue survivability as stem cells have been shown to increase angiogenesis and to minimize inflammatory responses.

Autologous fat transplantation which contains stem cells which can further differentiate in to mesenchymal stem cells is frequently used for a variety of cosmetic and reconstructive indications apart from post traumatic defects of the face and body, like as hemifacial atrophy, sequelae of radiation therapy, and many aesthetic uses such as lip and facial augmentation and anti-wrinkle therapy. Preclinical studies and early clinical studies show that adipose-derived stem cells offer the possibility of fulfilling the key principle of replacing with an aesthetic filler.


References:
http://en.wikipedia.org/wiki/Rhytidectomy

Timothy A. Moseley, Min Zhu, Marc H. Hedrick, Adipose-Derived Stem and Progenitor Cells as Fillers in Plastic and Reconstructive Surgery, Plastic and Reconstructive Surgery September 1 Supplement, 2006, Volume 118, Number 3S.

An Innovative Approach to Dermatological Rejuvenation as a result of Adipose Stem Cell Facial Transplantation and Platelet-Rich Fibrin Matrix, By Jeffry Schafer M.D., FRSM and Ron Shane PhD., OMD


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Breast Augmentation

Breast augmentation is a procedure for breasts enlargement or to restore breast volume. it also known as augmentation mammaplasty,

Although the mechanism of action of Adipose derived mesenchymal stem cells (Ad-MSCs) in a reconstructive capacity was not evaluated, many previous studies have demonstrated that Ad-MSCs contribute to increased microvascular density, accelerated neoangiogenesis and adipocyte differentiation, while preventing apoptosis by producing and releasing soluble angiogenic factors such as vascular endothelial growth factor, hepatocyte growth factor, and insulin-like growth factor-1

Emerging discoveries in stem cell biology have revealed a multitude of mechanisms through which MSC could potentially augment the current techniques in aesthetic surgery. Building on the clinical feasibility of using adipose- derived stem cell–supplemented fat as filler. The advantage of this procedure offers organic look, the soft and natural appering augmentation. Yoshimura and colleagues treated 40 patients with either demonstrable soft-tissue defects or breast augmentation using stem cell–supplemented fat transplantation for soft-tissue fill

References:
Timothy A. Moseley, Min Zhu, Marc H. Hedrick, Adipose-Derived Stem and Progenitor Cells as Fillers in Plastic and Reconstructive Surgery, Plastic and Reconstructive Surgery September 1 Supplement, 2006, Volume 118, Number 3S.

Summer E. Hanson, Karol A. Gutowski, Peiman Hematti, Clinical Applications of Mesenchymal Stem Cells in Soft Tissue Augmentation, Aesthetic Surgery Journal November/December 2010 vol. 30 no. 6, 838-842.

Myung-Soon Ko, Ji-Youl Jung, Il-Seob Shin, Eun-Wha Choi, Jae-Hoon Kim, Sung Keun Kang, Jeong Chan Ra, Effects of Expanded Human Adipose Tissue-Derived Mesenchymal Stem Cells on the Viability of Cryopreserved Fat Grafts in the Nude Mouse; International Journal off Medical Sciences 2011; 8(3):231-238.

 

Kotaro Yoshimura, 1 Katsujiro Sato,2 Noriyuki Aoi,1 Masakazu Kurita,3 Toshitsugu Hirohi,4 and Kiyonori Harii Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supportive Use of Adipose-Derived Stem/Stromal Cells Aesthetic Plast Surg. 2008 January; 32(1): 48–55


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